Peptide Stacking Cheat Sheet

One page, quick reference. Bookmark this page or print it for your protocol binder. Compatibility ratings are based on available research and community evidence — always verify against your specific situation.

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Key:

Pairs well — synergistic or complementary

Use with awareness — no direct conflict, but monitor

Avoid combining — competing mechanisms or no evidence

<\!-- ── RECOVERY ── -->

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Recovery — Injury, Tissue Repair & Inflammation

Goal: faster healing, reduced inflammation, tendon/ligament repair, muscle recovery

Peptide	Primary Role in Stack	Pairs With	Compatibility	Timing Note
BPC-157Core recovery agent	Tissue repair, anti-inflammatory, angiogenesis	TB-500	✓ Synergistic	BPC-157 AM · TB-500 any timeGold standard recovery combo — widely used together
TB-500Actin regulation, regeneration	Systemic recovery, angiogenesis, muscle repair	BPC-157	✓ Synergistic	2–3x/week · Monday/ThursdayDifferent mechanism — complements BPC-157 well
BPC-157	Gut lining + systemic healing	CJC-1295 + Ipamorelin	✓ Compatible	BPC-157 AM · GH secretagogues PM before sleepGH pulse supports recovery — space injections by 8+ hrs
BPC-157	Tissue repair	Semax / Selank	✓ Compatible	Different mechanisms — no interferenceUseful if injury comes with anxiety or cognitive stress
TB-500	Systemic regeneration	GHK-Cu	✓ Compatible	GHK-Cu for surface/skin healing, TB-500 for deeper tissueWorks well for post-surgical or multi-tissue recovery

Recovery Stack Protocol (example): BPC-157 250–500 mcg AM · TB-500 2.0–2.5 mg Monday + Thursday · CJC-1295 + Ipamorelin 200 mcg each, 30 min before sleep. Run for 6–8 weeks from injury onset.

<\!-- ── SKIN / ANTI-AGING ── -->

✨

Skin & Anti-Aging — Personal Aesthetic + Longevity

Goal: collagen synthesis, skin quality, cellular repair, wrinkle reduction, longevity markers

Peptide	Primary Role in Stack	Pairs With	Compatibility	Timing Note
GHK-CuCollagen synthesis anchor	Collagen/elastin production, wound healing, antioxidant	Epithalon	✓ Synergistic	GHK-Cu topical AM/PM · Epithalon subQ PMClassic longevity + skin combo — complementary mechanisms
EpithalonTelomere/pineal support	Cellular longevity, melatonin regulation, anti-aging	GHK-Cu	✓ Synergistic	10–20 day course, 1–2x/yearRun as periodic course — not continuous use
GHK-Cu	Collagen, skin repair	CJC-1295 + Ipamorelin	✓ Compatible	GH secretagogues amplify skin-relevant effects of GHGH promotes collagen — useful pairing for anti-aging
GHK-Cu topical	Surface skin application	High-dose Vitamin C (topical)	⚠ Caution	Separate by several hoursHigh-dose Vit C may reduce copper bioavailability — stagger timing
Epithalon	Cellular longevity	BPC-157	✓ Compatible	No known conflictsBPC-157 adds gut + systemic repair during Epithalon course

Anti-Aging Stack Protocol (example): GHK-Cu topical 1–2% AM + PM · CJC-1295 + Ipamorelin 200 mcg each PM before sleep · Epithalon 5–10 mg/day PM for 14-day course in spring + fall.

<\!-- ── COGNITIVE ── -->

🧠

Cognitive — Focus, Memory & Mood

Goal: enhanced focus, reduced anxiety, BDNF support, mental clarity, stress resilience

Peptide	Primary Role in Stack	Pairs With	Compatibility	Timing Note
SemaxBDNF, focus, neuroprotection	Cognitive enhancement, memory, BDNF upregulation	Selank	✓ Synergistic	Semax AM (stimulating) · Selank AM or as-needed (calming)Selank balances Semax's stimulating edge — classic combo
SelankAnxiolytic, mood stabilizer	Anxiety reduction, GABAergic modulation	Semax	✓ Synergistic	Can use same session or stagger AMDifferent mechanisms — no receptor competition
Semax	Focus enhancement	BPC-157 (oral)	✓ Compatible	BPC-157 oral for gut-brain axis supportGut health affects cognitive performance — useful combo
Semax	CNS stimulation	Racetams / stimulants (caffeine + high dose)	⚠ Caution	Reduce stimulants when using SemaxAdditive stimulation — can cause overstimulation or anxiety
Selank	Anxiety, mood	CJC-1295 + Ipamorelin	✓ Compatible	Selank AM · GH secretagogues PM before sleepGH quality sleep amplifies cognitive benefit of Selank

Cognitive Stack Protocol (example): Semax 300–600 mcg intranasal AM · Selank 250–500 mcg intranasal AM (or pre-stressor) · Cycle: 3 weeks on, 1 week off. Avoid late-day dosing — Semax is stimulating.

<\!-- ── GUT HEALTH ── -->

🌱

Gut Health — Repair, IBS, Leaky Gut

Goal: gut lining repair, motility, inflammation reduction, microbiome support

Peptide	Primary Role in Stack	Pairs With	Compatibility	Timing Note
BPC-157 (oral)Gut lining anchor	Mucosa repair, motility, anti-inflammatory in gut	Selank	✓ Compatible	BPC-157 oral AM fasted · Selank for gut-anxiety linkGut-brain axis — anxiety often worsens gut symptoms
BPC-157 (oral)	Gut healing	TB-500	✓ Compatible	TB-500 subQ for systemic support alongside oral BPCTB-500 adds systemic regeneration while BPC targets gut locally
BPC-157 (oral)	Gut lining	NSAIDs / alcohol	✗ Avoid	NSAIDs damage gut lining — counteracts BPC-157Pause NSAIDs during gut healing protocol if possible
BPC-157 (oral)	Gut healing	KPV	✓ Compatible	KPV specifically for IBD/Crohn's — pair with BPC-157 for broad gut supportBoth oral, different anti-inflammatory mechanisms

Gut Healing Protocol (example): BPC-157 250–500 mcg oral on empty stomach AM · Selank 250 mcg intranasal as needed for stress/anxiety · 8–12 week course. Reduce processed food, alcohol, and NSAIDs during protocol.

If you have active IBD, Crohn's, or ulcerative colitis: these are research compounds, not treatments. Consult your gastroenterologist before adding any peptide protocol alongside existing treatment.

<\!-- ── FAT LOSS ── -->

⚡

Fat Loss & Body Composition

Goal: body recomposition, fat oxidation, lean mass preservation, metabolic support

Peptide	Primary Role in Stack	Pairs With	Compatibility	Timing Note
CJC-1295 + IpamorelinGH pulse amplification	GH-mediated lipolysis, lean mass preservation	BPC-157	✓ Compatible	GH secretagogues PM · BPC-157 AMBPC-157 supports recovery from training volume
CJC-1295 + Ipamorelin	GH pulse, body composition	High-carb meals before injection	✗ Avoid	Insulin blunts GH releaseAlways inject fasted — minimum 2 hrs after last carb-containing meal
CJC-1295 + Ipamorelin	GH secretagogue	Epithalon	✓ Compatible	PM before sleep for bothEpithalon course (periodic) alongside ongoing GH secretagogue protocol
TB-500	Recovery, maintains training output	CJC-1295 + Ipamorelin	✓ Compatible	Training recovery enables higher volume → better body composition outcomesSupports the exercise necessary for composition change
AOD-9604GH fragment	Direct lipolysis, no IGF-1 impact	CJC-1295 + Ipamorelin	⚠ Research ongoing	AOD-9604: 250–300 mcg AM fastedLess data on combined use — monitor for overlapping GH axis effects

Body Composition Protocol (example): CJC-1295 200 mcg + Ipamorelin 200 mcg subQ 30–60 min before sleep (fasted) · TB-500 2.0 mg 2x/week for recovery · Training: resistance + cardiovascular on non-fasted windows. 12–16 week cycle.

Medical Disclaimer: This cheat sheet is for educational and research reference only. Compatibility ratings reflect available literature and community practice — not clinical validation. Peptides referenced are research chemicals; none are FDA-approved for human use. Nothing here is medical advice. Consult a qualified healthcare provider before starting any peptide protocol.

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